Many prescription drug bottles and pills

What is Tramadol and Why It’s on the Controlled Substance List

You may know tramadol under its brand name, Ultram. Manufacturers also offer an extended release version, Ultram ER. When mixed with acetaminophen, which sells under the trade name Tylenol, the drug’s name changes to Ultracet. But what is tramadol, exactly? Opioid Painkiller or Serotonin Uptake Inhibitor? Both! Initially, the manufacturer believed that the substance had…